node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B4135_2975 | ddl | B4135_2975 | B4135_4122 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.558 |
B4135_2975 | divIB | B4135_2975 | B4135_2973 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | Hypothetical protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.853 |
B4135_2975 | ftsZ | B4135_2975 | B4135_2968 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | Hypothetical protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.615 |
B4135_2975 | mraY | B4135_2975 | B4135_2977 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.918 |
B4135_2975 | murC | B4135_2975 | B4135_3059 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.820 |
B4135_2975 | murD | B4135_2975 | B4135_2976 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.970 |
B4135_2975 | murE | B4135_2975 | B4135_2978 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.764 |
B4135_2975 | murF | B4135_2975 | B4135_4121 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.776 |
B4135_2975 | murG | B4135_2975 | B4135_2974 | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.952 |
ddl | B4135_2975 | B4135_4122 | B4135_2975 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | 0.558 |
ddl | divIB | B4135_4122 | B4135_2973 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.813 |
ddl | ftsW | B4135_4122 | B4135_2783 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Cell division protein FtsW; Belongs to the SEDS family. | 0.686 |
ddl | ftsZ | B4135_4122 | B4135_2968 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hypothetical protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.405 |
ddl | mraY | B4135_4122 | B4135_2977 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.714 |
ddl | murC | B4135_4122 | B4135_3059 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.993 |
ddl | murD | B4135_4122 | B4135_2976 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.934 |
ddl | murE | B4135_4122 | B4135_2978 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.848 |
ddl | murF | B4135_4122 | B4135_4121 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.995 |
ddl | murG | B4135_4122 | B4135_2974 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.808 |
divIB | B4135_2975 | B4135_2973 | B4135_2975 | Hypothetical protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | Cell division protein FtsW / Stage V sporulation protein E; Belongs to the SEDS family. | 0.853 |