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CTU1 protein (Chlamydomonas reinhardtii) - STRING interaction network
"CTU1" - Adenine nucleotide hydrolase in Chlamydomonas reinhardtii
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CTU1Adenine nucleotide hydrolase; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (357 aa)    
Predicted Functional Partners:
URM1
Ubiquitin-related modifier; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically [...] (99 aa)
       
  0.759
PROB1
Glutamate 5-kinase (519 aa)
         
  0.730
PROB2
Glutamate 5-kinase (775 aa)
         
  0.730
nad4
NADH dehydrogenase subunit 4 (443 aa)
         
  0.712
EDO97260
Histone acetyltransferase (322 aa)
     
 
  0.700
RPS3
Ribosomal protein S3 (230 aa)
           
  0.596
rps3
Ribosomal protein S3 (712 aa)
           
  0.593
nad5
NADH dehydrogenase subunit 5 (546 aa)
     
 
  0.589
FAP42
Flagellar associated protein, adenylate/guanylate kinase-like protein (2457 aa)
       
  0.550
FTSH3
Membrane AAA-metalloprotease (752 aa)
     
 
  0.542
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonadaceae, Chlamydomonadales, Chlamydomonas, Chlamydomonas reinhardtii, Chlamydomonas reinhardtii P.A.Dangeard, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, Chlorophyceae, Volvocales, Volvocida
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