STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THI1Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Bel [...] (357 aa)    
Predicted Functional Partners:
THICb
Hydroxymethylpyrimidine phosphate synthase
  
  
 0.966
THI10
Hydroxyethylthiazole kinase; THI10p
     
 0.908
TPK1
Thiamine pyrophosphokinase
      
 0.898
EDP09073
Predicted protein
      
 0.856
RECA
Chloroplast RecA recombination protein ; Belongs to the RecA family
      
 0.848
EDP05682
Predicted protein
   
  
 0.819
CEP1
Cysteine endopeptidase ; Belongs to the peptidase C1 family
      
 0.751
EDP08963
Predicted protein
      
 0.745
EDO99335
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione
      
 0.652
VTE3
MPBQ/MSBQ methyltransferase; Plant-type MPBQ/MSBQ methyltransferase
  
  
 0.602
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonas reinhardtii, Chlamydomonas reinhardtii P.A.Dangeard, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, SAG 53.72 [[Chlamydomonas smithii]], SAG 54.72 [[Chlamydomonas smithii]], UTEX 90
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