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THI1 protein (Chlamydomonas reinhardtii) - STRING interaction network
"THI1" - Full-length thiazole biosynthetic enzyme in Chlamydomonas reinhardtii
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second shell of interactors
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filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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THI1Full-length thiazole biosynthetic enzyme; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance (357 aa)    
Predicted Functional Partners:
MPA1
Metallophosphoesterase, phosphate-repressible (402 aa)
           
  0.778
THICa
Hydroxymethylpyrimidine phosphate synthase (637 aa)
   
   
  0.673
RECA
Chloroplast RecA recombination protein (415 aa)
         
  0.616
DAE1
Diaminopimelate epimerase (318 aa)
         
  0.581
CPA2
N-carbamoylputrescine amidase (292 aa)
           
  0.571
EDP05682
Predicted protein (357 aa)
     
   
  0.559
CGL41
Predicted protein (201 aa)
     
      0.500
RPS13
Ribosomal protein S13 (151 aa)
           
  0.499
FTSY
Chloroplast SRP receptor (338 aa)
         
  0.499
PYR5
Uridine 5’-monophosphate synthase (474 aa)
         
  0.457
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonadaceae, Chlamydomonadales, Chlamydomonas, Chlamydomonas reinhardtii, Chlamydomonas reinhardtii P.A.Dangeard, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, Chlorophyceae, Volvocales, Volvocida
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