STRINGSTRING
PF2 protein (Chlamydomonas reinhardtii) - STRING interaction network
"PF2" - Component of dynein regulatory complex in Chlamydomonas reinhardtii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF2Component of dynein regulatory complex (471 aa)    
Predicted Functional Partners:
PF9
Flagellar inner arm dynein 1 heavy chain alpha (4625 aa)
     
   
  0.882
RSP3
Radial spoke protein 3 (516 aa)
     
   
  0.868
DRC3
Flagellar associated protein; Key component of the nexin-dynein regulatory complex (N- DRC). Requires for normal flagellar waveform (524 aa)
     
   
  0.854
PF20
WD-repeat protein of flagellum central pair (521 aa)
     
   
  0.846
FAP59
Flagellar associated protein; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, by acting as a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (PubMed-25395538). Together with CCDC40/FAP172 forms a 96-nm-long complex in flagella. This complex does not act as a physical ruler, but rather act as a negative regulator for radial spokes- the complex lays along specific protofilaments, masking radial spoke binding sites and allowin [...] (894 aa)
     
   
  0.841
ODA1
Flagellar outer dynein arm-docking complex protein 2; Component of the outer dynein arm complex required for assembly of the outer dynein arm-docking complex (ODA-DC) and the outer dynein arm onto the doublet microtubule (552 aa)
     
   
  0.796
FAP252
Flagellar associated protein (352 aa)
     
   
  0.787
FAP119
Flagellar associated protein (306 aa)
     
   
  0.785
EDP05194
Dynein heavy chain (5013 aa)
     
   
  0.780
RSP11
Radial spoke protein 11 (204 aa)
     
   
  0.779
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonadaceae, Chlamydomonadales, Chlamydomonas, Chlamydomonas reinhardtii, Chlamydomonas reinhardtii P.A.Dangeard, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, Chlorophyceae, Volvocales, Volvocida
Server load: low (7%) [HD]