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PDE6 protein (Chlamydomonas reinhardtii) - STRING interaction network
"PDE6" - 3',5'-cyclic-nucleotide phosphodiesterase in Chlamydomonas reinhardtii
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE63’,5’-cyclic-nucleotide phosphodiesterase (297 aa)    
Predicted Functional Partners:
ARL13
ARF-like GTPase; Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B (By similarity) (527 aa)
     
   
  0.846
ARL3
ARF-like GTPase; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium (185 aa)
           
  0.807
ARL2
ARF-like GTPase (184 aa)
           
  0.801
XPO1
Exportin (1075 aa)
           
  0.780
SMC3
Structural maintenance of chromosomes protein 3 (1121 aa)
           
  0.775
SMC1
Structural maintenance of chromosomes protein 1 (818 aa)
           
  0.775
VPS9
Guanine nucleotide exchange factor (495 aa)
           
  0.721
FAP290
Flagellar associated protein (339 aa)
     
  0.667
DLC4
Flagellar outer dynein arm 18 kDa light chain LC4 (159 aa)
     
  0.627
EDP10024
Predicted protein (272 aa)
     
  0.624
Your Current Organism:
Chlamydomonas reinhardtii
NCBI taxonomy Id: 3055
Other names: C. reinhardtii, Chlamydomonadaceae, Chlamydomonadales, Chlamydomonas, Chlamydomonas reinhardtii, Chlamydomonas reinhardtii P.A.Dangeard, Chlamydomonas smithii, Chlamydomonas smithii R.W.Howshaw & H.Ettl, Chlorophyceae, Volvocales, Volvocida
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