Groups of genes that are frequently observed in each other's genomic neighborhood.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Predicted protein (528 aa)
Predicted Functional Partners:
Glycine rich protein (1032 aa)
Plastid-specific ribosomal protein 7; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (1013 aa)
Separase, cell cycle protease (2337 aa)
Global transcription factor (1054 aa)
Paf1 complex component (973 aa)
Predicted protein (348 aa)
Global transcription factor (1188 aa)
DNA-directed RNA polymerase II, 135 kDa polypeptide; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1634 aa)
RNA polymerase beta subunit I; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (822 aa)
RNA polymerase beta subunit II; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (626 aa)