STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYCNMYCN proto-oncogene, bHLH transcription factor. (437 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A.
    
 
 0.986
MAX
MYC associated factor X.
    
0.984
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.931
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.931
SCAP
SREBF chaperone.
   
 0.931
KPNB1
Karyopherin subunit beta 1.
    
 0.913
MYC
MYC proto-oncogene, bHLH transcription factor.
    
0.880
MNT
MAX network transcriptional repressor.
    
 0.836
SIRT6
Sirtuin 6.
    
 0.827
MBTPS2
Membrane bound transcription factor peptidase, site 2.
    
 0.820
Your Current Organism:
Microcebus murinus
NCBI taxonomy Id: 30608
Other names: M. murinus, gray mouse lemur, grey mouse lemur
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.