STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAF3IP2TRAF3 interacting protein 2. (565 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.936
IL17RA
Interleukin 17 receptor A.
    
 0.923
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.860
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.831
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.802
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.799
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.762
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.749
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.709
INPPL1
Inositol polyphosphate phosphatase like 1.
    
  0.695
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.