NFATC1 protein (Otolemur garnettii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NFATC1

Nuclear factor of activated T cells 1. (929 aa)

Predicted Functional Partners:

PPP3CA

0.991

H0XZZ5_OTOGA

0.987

PPP3CB

0.957

PPP3CC

0.957

MAPK9

0.947

MAPK8

0.925

MAPK10

0.925

NFATC2

0.899

GATA4

0.870

GSK3B

0.863

Your Current Organism:

Otolemur garnettii

NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GATA4	NFATC1	ENSOGAP00000016128	ENSOGAP00000007303	GATA binding protein 4.	Nuclear factor of activated T cells 1.	0.870
GATA4	NFATC2	ENSOGAP00000016128	ENSOGAP00000012352	GATA binding protein 4.	Nuclear factor of activated T cells 2.	0.873
GSK3B	H0XZZ5_OTOGA	ENSOGAP00000005385	ENSOGAP00000021688	Glycogen synthase kinase 3 beta.	Uncharacterized protein.	0.871
GSK3B	NFATC1	ENSOGAP00000005385	ENSOGAP00000007303	Glycogen synthase kinase 3 beta.	Nuclear factor of activated T cells 1.	0.863
GSK3B	NFATC2	ENSOGAP00000005385	ENSOGAP00000012352	Glycogen synthase kinase 3 beta.	Nuclear factor of activated T cells 2.	0.850
GSK3B	PPP3CA	ENSOGAP00000005385	ENSOGAP00000010172	Glycogen synthase kinase 3 beta.	Serine/threonine-protein phosphatase.	0.909
GSK3B	PPP3CB	ENSOGAP00000005385	ENSOGAP00000001945	Glycogen synthase kinase 3 beta.	Serine/threonine-protein phosphatase.	0.913
GSK3B	PPP3CC	ENSOGAP00000005385	ENSOGAP00000009457	Glycogen synthase kinase 3 beta.	Serine/threonine-protein phosphatase.	0.920
H0XZZ5_OTOGA	GSK3B	ENSOGAP00000021688	ENSOGAP00000005385	Uncharacterized protein.	Glycogen synthase kinase 3 beta.	0.871
H0XZZ5_OTOGA	NFATC1	ENSOGAP00000021688	ENSOGAP00000007303	Uncharacterized protein.	Nuclear factor of activated T cells 1.	0.987
H0XZZ5_OTOGA	NFATC2	ENSOGAP00000021688	ENSOGAP00000012352	Uncharacterized protein.	Nuclear factor of activated T cells 2.	0.927
H0XZZ5_OTOGA	PPP3CA	ENSOGAP00000021688	ENSOGAP00000010172	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.997
H0XZZ5_OTOGA	PPP3CB	ENSOGAP00000021688	ENSOGAP00000001945	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.994
H0XZZ5_OTOGA	PPP3CC	ENSOGAP00000021688	ENSOGAP00000009457	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.989
MAPK10	MAPK9	ENSOGAP00000013344	ENSOGAP00000015111	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.975
MAPK10	NFATC1	ENSOGAP00000013344	ENSOGAP00000007303	Mitogen-activated protein kinase.	Nuclear factor of activated T cells 1.	0.925
MAPK10	NFATC2	ENSOGAP00000013344	ENSOGAP00000012352	Mitogen-activated protein kinase.	Nuclear factor of activated T cells 2.	0.856
MAPK8	MAPK9	ENSOGAP00000007309	ENSOGAP00000015111	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.975
MAPK8	NFATC1	ENSOGAP00000007309	ENSOGAP00000007303	Mitogen-activated protein kinase.	Nuclear factor of activated T cells 1.	0.925
MAPK8	NFATC2	ENSOGAP00000007309	ENSOGAP00000012352	Mitogen-activated protein kinase.	Nuclear factor of activated T cells 2.	0.856