STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL14EPADP ribosylation factor like GTPase 14 effector protein. (260 aa)    
Predicted Functional Partners:
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
    
 
 0.923
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
    
 
 0.923
ATF7IP
Activating transcription factor 7 interacting protein.
  
 
 
 0.901
LOC100952166
Fibronectin type-III domain-containing protein.
    
 
 0.814
H0XFA2_OTOGA
ATF7IP_BD domain-containing protein.
    
 
 0.814
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
   0.666
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
   0.666
MED21
Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
    0.596
SUOX
Sulfite oxidase.
      
 0.594
OSCP1
Organic solute carrier partner 1.
      
 0.538
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.