STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STAT5BSignal transducer and activator of transcription. (788 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.947
EGFR
Receptor protein-tyrosine kinase.
    
 0.942
JAK1
Tyrosine-protein kinase.
   
 0.942
IRF9
Interferon regulatory factor 9.
   
 0.941
JAK3
Tyrosine-protein kinase.
   
 0.940
TYK2
Tyrosine-protein kinase.
   
 0.939
CREBBP
CREB binding protein.
    
 0.909
PIAS3
Protein inhibitor of activated STAT 3.
    
 0.896
EP300
E1A binding protein p300.
    
 0.890
IL2RA
Interleukin 2 receptor subunit alpha.
    
 0.889
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.