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ATXN7L3 protein (Otolemur garnettii) - STRING interaction network
"ATXN7L3" - Ataxin-7-like protein 3 in Otolemur garnettii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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Experiments
Databases
Textmining
[Homology]
Score
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)    
Predicted Functional Partners:
TADA3
Transcriptional adaptor 3 (432 aa)
       
  0.958
SUPT3H
SPT3 homolog, SAGA and STAGA complex component; Suppressor of Ty 3 homolog (S. cerevisiae) (242 aa)
     
  0.956
ENY2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
     
  0.954
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa (162 aa)
     
  0.950
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors (218 aa)
     
  0.949
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa (258 aa)
     
  0.949
TADA2B
Transcriptional adaptor 2B (420 aa)
       
  0.945
ENSOGAG00000034571
Uncharacterized protein (280 aa)
     
  0.944
ENSOGAG00000015794
annotation not available (293 aa)
     
  0.944
ATXN7L1
Ataxin 7-like 1 (846 aa)
       
  0.937
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, Otolemur garnettii, small-eared galago
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