STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (948 aa)    
Predicted Functional Partners:
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.986
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.984
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.981
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.981
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.970
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.961
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.951
TRAF1
TNF receptor-associated factor.
    
 0.943
NFKB2
Nuclear factor kappa B subunit 2.
   
 0.910
LTBR
Lymphotoxin beta receptor.
    
 0.894
Your Current Organism:
Otolemur garnettii
NCBI taxonomy Id: 30611
Other names: Galago garnetti, Galago garnettii, O. garnettii, small-eared galago
Server load: low (30%) [HD]