node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
coaA | dfp | jk1466 | jk1017 | Pantothenate kinase (EC 2.7.1.33) (Pantothenic acid kinase). | Phosphopantothenate cysteine ligase / 4'-phospho-pantothenoyl-cysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.944 |
coaA | panC | jk1466 | jk0286 | Pantothenate kinase (EC 2.7.1.33) (Pantothenic acid kinase). | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.928 |
dfp | coaA | jk1017 | jk1466 | Phosphopantothenate cysteine ligase / 4'-phospho-pantothenoyl-cysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase (EC 2.7.1.33) (Pantothenic acid kinase). | 0.944 |
dfp | panB | jk1017 | jk0674 | Phosphopantothenate cysteine ligase / 4'-phospho-pantothenoyl-cysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.515 |
dfp | panC | jk1017 | jk0286 | Phosphopantothenate cysteine ligase / 4'-phospho-pantothenoyl-cysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.879 |
folE | folK | jk0279 | jk0282 | GTP cyclohydrolase I. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | 0.997 |
folE | folP | jk0279 | jk0280 | GTP cyclohydrolase I. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folE | jk0284 | jk0279 | jk0284 | GTP cyclohydrolase I. | Hypothetical protein. | 0.807 |
folE | jk0285 | jk0279 | jk0285 | GTP cyclohydrolase I. | Hypothetical protein. | 0.800 |
folE | panC | jk0279 | jk0286 | GTP cyclohydrolase I. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.819 |
folK | folE | jk0282 | jk0279 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | GTP cyclohydrolase I. | 0.997 |
folK | folP | jk0282 | jk0280 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folK | jk0284 | jk0282 | jk0284 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Hypothetical protein. | 0.807 |
folK | jk0285 | jk0282 | jk0285 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Hypothetical protein. | 0.800 |
folK | panC | jk0282 | jk0286 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.839 |
folP | folE | jk0280 | jk0279 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I. | 0.999 |
folP | folK | jk0280 | jk0282 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. | 0.999 |
folP | jk0284 | jk0280 | jk0284 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein. | 0.807 |
folP | jk0285 | jk0280 | jk0285 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein. | 0.800 |
folP | panC | jk0280 | jk0286 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.851 |