node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bioB | birA | jk0682 | jk1661 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin-protein ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)].,BirA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor acetyl-CoA:carbon- dioxide ligase. This protein also activates biotin to form biotinyl-5-adenylate and transfers the biotin moiety to biotin-accepting proteins (By similarity). | 0.971 |
bioB | fpr1 | jk0682 | jk0242 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative ferredoxin/ferredoxin-NADP reductase; NADPH-ferredoxin reductase (EC 1.18.1.2) (NFR). | 0.459 |
bioB | jk0679 | jk0682 | jk0679 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative membrane protein. | 0.461 |
bioB | jk0680 | jk0682 | jk0680 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Hypothetical protein. | 0.476 |
bioB | jk0681 | jk0682 | jk0681 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Hypothetical protein. | 0.935 |
bioB | jk1118 | jk0682 | jk1118 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative BioY family protein. | 0.520 |
bioB | lipA | jk0682 | jk0705 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.439 |
bioB | nadE | jk0682 | jk0474 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | NAD-synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.593 |
bioB | ribD | jk0682 | jk1010 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.533 |
bioB | thiC | jk0682 | jk0855 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.502 |
birA | bioB | jk1661 | jk0682 | Biotin-protein ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)].,BirA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor acetyl-CoA:carbon- dioxide ligase. This protein also activates biotin to form biotinyl-5-adenylate and transfers the biotin moiety to biotin-accepting proteins (By similarity). | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.971 |
birA | jk1118 | jk1661 | jk1118 | Biotin-protein ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)].,BirA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor acetyl-CoA:carbon- dioxide ligase. This protein also activates biotin to form biotinyl-5-adenylate and transfers the biotin moiety to biotin-accepting proteins (By similarity). | Putative BioY family protein. | 0.629 |
birA | nadE | jk1661 | jk0474 | Biotin-protein ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)].,BirA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor acetyl-CoA:carbon- dioxide ligase. This protein also activates biotin to form biotinyl-5-adenylate and transfers the biotin moiety to biotin-accepting proteins (By similarity). | NAD-synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.482 |
birA | ribD | jk1661 | jk1010 | Biotin-protein ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)].,BirA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor acetyl-CoA:carbon- dioxide ligase. This protein also activates biotin to form biotinyl-5-adenylate and transfers the biotin moiety to biotin-accepting proteins (By similarity). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.491 |
fpr1 | bioB | jk0242 | jk0682 | Putative ferredoxin/ferredoxin-NADP reductase; NADPH-ferredoxin reductase (EC 1.18.1.2) (NFR). | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.459 |
jk0679 | bioB | jk0679 | jk0682 | Putative membrane protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.461 |
jk0679 | jk0680 | jk0679 | jk0680 | Putative membrane protein. | Hypothetical protein. | 0.741 |
jk0679 | jk0681 | jk0679 | jk0681 | Putative membrane protein. | Hypothetical protein. | 0.487 |
jk0680 | bioB | jk0680 | jk0682 | Hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.476 |
jk0680 | jk0679 | jk0680 | jk0679 | Hypothetical protein. | Putative membrane protein. | 0.741 |