STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa)    
Predicted Functional Partners:
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.999
hom
Homoserine dehydrogenase (EC 1.1.1.3) (HDH).
 
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase).
 
    
 0.905
metE
Methionine synthase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.869
metB
Cystathionine gamma-synthase (EC 2.5.1.48) (CGS) (O-succinylhomoserine (Thiol)-lyase).
  
 
 0.855
sdaA
L-serine dehydratase.
  
 
 0.831
ilvE
Branched-chain amino acid aminotransferase.
  
 
 0.827
cysE
Serine acetyltransferase (EC 2.3.1.30) (SAT).
     
 0.821
cysY
Cystathionine beta-synthase.
     
 0.812
metY
O-acetylhomoserine (thiol)-lyase; Cystathionine gamma-lyase (EC 4.4.1.1) (Gamma-cystathionase).
    
  0.810
Your Current Organism:
Corynebacterium jeikeium
NCBI taxonomy Id: 306537
Other names: C. jeikeium K411, Corynebacterium jeikeium K411, Corynebacterium jeikeium str. K411, Corynebacterium jeikeium strain K411
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.