node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccdA | ccsX | jk1892 | jk1893 | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | Thiol-disulfide isomerase/thioredoxin. | 0.998 |
ccdA | ctaE | jk1892 | jk0719 | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | Probable cytochrome c oxidase polypeptide III (EC 1.9.3.1) (Cytochrome AA3 subunit 3). | 0.769 |
ccdA | hemA | jk1892 | jk1902 | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.865 |
ccdA | hemB | jk1892 | jk1899 | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | Porphobilinogen synthase; Delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH); Belongs to the ALAD family. | 0.602 |
ccdA | hemD | jk1892 | jk1900 | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Porphyrin biosynthesis protein HEMD [Includes: Uroporphyrin-III C- methyltransferase (EC 2.1.1.107) (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen-III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing])].,May catalyze sequential reactions to synthesize UroIII from hydroxymethylbilane (HMB) and then precorrin-2 which are intermediate compounds in both vitamin B12 and siroheme biosyntheses. | 0.699 |
ccdA | hemE | jk1892 | jk1075 | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.888 |
ccdA | hemL | jk1892 | jk1895 | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | Glutamate-1-semialdehyde 21-aminomutase (EC 5.4.3.8) (GSA) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT). | 0.960 |
ccsX | ccdA | jk1893 | jk1892 | Thiol-disulfide isomerase/thioredoxin. | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | 0.998 |
ccsX | ctaE | jk1893 | jk0719 | Thiol-disulfide isomerase/thioredoxin. | Probable cytochrome c oxidase polypeptide III (EC 1.9.3.1) (Cytochrome AA3 subunit 3). | 0.825 |
ccsX | hemA | jk1893 | jk1902 | Thiol-disulfide isomerase/thioredoxin. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.918 |
ccsX | hemB | jk1893 | jk1899 | Thiol-disulfide isomerase/thioredoxin. | Porphobilinogen synthase; Delta-aminolevulinic acid dehydratase (EC 4.2.1.24) (Porphobilinogen synthase) (ALAD) (ALADH); Belongs to the ALAD family. | 0.635 |
ccsX | hemC | jk1893 | jk1901 | Thiol-disulfide isomerase/thioredoxin. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.406 |
ccsX | hemD | jk1893 | jk1900 | Thiol-disulfide isomerase/thioredoxin. | uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase; Porphyrin biosynthesis protein HEMD [Includes: Uroporphyrin-III C- methyltransferase (EC 2.1.1.107) (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); Uroporphyrinogen-III synthase (EC 4.2.1.75) (UROS) (Uroporphyrinogen-III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing])].,May catalyze sequential reactions to synthesize UroIII from hydroxymethylbilane (HMB) and then precorrin-2 which are intermediate compounds in both vitamin B12 and siroheme biosyntheses. | 0.687 |
ccsX | hemE | jk1893 | jk1075 | Thiol-disulfide isomerase/thioredoxin. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.944 |
ccsX | hemL | jk1893 | jk1895 | Thiol-disulfide isomerase/thioredoxin. | Glutamate-1-semialdehyde 21-aminomutase (EC 5.4.3.8) (GSA) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT). | 0.992 |
ctaE | ccdA | jk0719 | jk1892 | Probable cytochrome c oxidase polypeptide III (EC 1.9.3.1) (Cytochrome AA3 subunit 3). | Cytochrome c-type biogenesis protein ccdA.,Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat (By similarity). | 0.769 |
ctaE | ccsX | jk0719 | jk1893 | Probable cytochrome c oxidase polypeptide III (EC 1.9.3.1) (Cytochrome AA3 subunit 3). | Thiol-disulfide isomerase/thioredoxin. | 0.825 |
ctaE | hemA | jk0719 | jk1902 | Probable cytochrome c oxidase polypeptide III (EC 1.9.3.1) (Cytochrome AA3 subunit 3). | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.831 |
ctaE | hemE | jk0719 | jk1075 | Probable cytochrome c oxidase polypeptide III (EC 1.9.3.1) (Cytochrome AA3 subunit 3). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.633 |
ctaE | hemL | jk0719 | jk1895 | Probable cytochrome c oxidase polypeptide III (EC 1.9.3.1) (Cytochrome AA3 subunit 3). | Glutamate-1-semialdehyde 21-aminomutase (EC 5.4.3.8) (GSA) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT). | 0.931 |