STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OCT1Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity). (778 aa)    
Predicted Functional Partners:
CHGG_02593
M16C_associated domain-containing protein.
    
 
 0.610
CHGG_10532
Uncharacterized protein.
   
 
 0.605
CHGG_09087
AMP_N domain-containing protein.
   
 
 0.601
CHGG_06224
Arg-6 protein, mitochondrial; In the N-terminal section; belongs to the acetylglutamate kinase family.
      
 0.595
CHGG_03089
Uncharacterized protein; Belongs to the peptidase M16 family.
   
  
 0.595
CHGG_01367
Uncharacterized protein; Belongs to the peptidase M16 family.
   
  
 0.593
CHGG_02813
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
   
  
 0.588
ATP23
Mitochondrial inner membrane protease ATP23; Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity); Belongs to the peptidase M76 family.
      
 0.586
CHGG_03393
Lactamase_B domain-containing protein.
  
  
 0.571
CHGG_09111
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
      
 0.565
Your Current Organism:
Chaetomium globosum
NCBI taxonomy Id: 306901
Other names: C. globosum CBS 148.51, Chaetomium globosum CBS 148.51
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