node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACI16802.1 | ACI17852.1 | COPRO5265_0818 | COPRO5265_0817 | 2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
ACI16802.1 | clpP | COPRO5265_0818 | COPRO5265_0814 | 2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.800 |
ACI16802.1 | clpX | COPRO5265_0818 | COPRO5265_0815 | 2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.774 |
ACI16802.1 | lon | COPRO5265_0818 | COPRO5265_0816 | 2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.777 |
ACI16802.1 | tig | COPRO5265_0818 | COPRO5265_0813 | 2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Trigger factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.783 |
ACI17852.1 | ACI16802.1 | COPRO5265_0817 | COPRO5265_0818 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
ACI17852.1 | clpP | COPRO5265_0817 | COPRO5265_0814 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.773 |
ACI17852.1 | clpX | COPRO5265_0817 | COPRO5265_0815 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.773 |
ACI17852.1 | lon | COPRO5265_0817 | COPRO5265_0816 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.773 |
ACI17852.1 | tig | COPRO5265_0817 | COPRO5265_0813 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Trigger factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
clpP | ACI16802.1 | COPRO5265_0814 | COPRO5265_0818 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
clpP | ACI17852.1 | COPRO5265_0814 | COPRO5265_0817 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
clpP | clpX | COPRO5265_0814 | COPRO5265_0815 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.998 |
clpP | dnaJ | COPRO5265_0814 | COPRO5265_0354 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.567 |
clpP | dnaK | COPRO5265_0814 | COPRO5265_0355 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.737 |
clpP | ftsH | COPRO5265_0814 | COPRO5265_0915 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.430 |
clpP | groEL | COPRO5265_0814 | COPRO5265_0636 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.687 |
clpP | grpE | COPRO5265_0814 | COPRO5265_1107 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.699 |
clpP | lon | COPRO5265_0814 | COPRO5265_0816 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.926 |
clpP | tig | COPRO5265_0814 | COPRO5265_0813 | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Trigger factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.875 |