node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACI17687.1 | ACI17880.1 | COPRO5265_1206 | COPRO5265_1352 | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.941 |
ACI17687.1 | ACI18052.1 | COPRO5265_1206 | COPRO5265_1289 | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.921 |
ACI17687.1 | gcvPA | COPRO5265_1206 | COPRO5265_1070 | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.908 |
ACI17687.1 | gcvPB | COPRO5265_1206 | COPRO5265_1069 | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.916 |
ACI17687.1 | glyA | COPRO5265_1206 | COPRO5265_0715 | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.930 |
ACI17687.1 | glyA1 | COPRO5265_1206 | COPRO5265_0160 | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.911 |
ACI17880.1 | ACI17687.1 | COPRO5265_1352 | COPRO5265_1206 | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.941 |
ACI17880.1 | ACI18052.1 | COPRO5265_1352 | COPRO5265_1289 | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.916 |
ACI17880.1 | gcvPA | COPRO5265_1352 | COPRO5265_1070 | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.902 |
ACI17880.1 | gcvPB | COPRO5265_1352 | COPRO5265_1069 | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.916 |
ACI17880.1 | glyA | COPRO5265_1352 | COPRO5265_0715 | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.934 |
ACI17880.1 | glyA1 | COPRO5265_1352 | COPRO5265_0160 | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
ACI18009.1 | ACI18052.1 | COPRO5265_0140 | COPRO5265_1289 | Biotin synthase; Catalyzes the formation of biotin from dethiobiotin and sulfur; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.815 |
ACI18052.1 | ACI17687.1 | COPRO5265_1289 | COPRO5265_1206 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
ACI18052.1 | ACI17880.1 | COPRO5265_1289 | COPRO5265_1352 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
ACI18052.1 | ACI18009.1 | COPRO5265_1289 | COPRO5265_0140 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Biotin synthase; Catalyzes the formation of biotin from dethiobiotin and sulfur; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.815 |
ACI18052.1 | fabF | COPRO5265_1289 | COPRO5265_0253 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.784 |
ACI18052.1 | gcvPA | COPRO5265_1289 | COPRO5265_1070 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.918 |
ACI18052.1 | gcvPB | COPRO5265_1289 | COPRO5265_1069 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.919 |
ACI18052.1 | glyA | COPRO5265_1289 | COPRO5265_0715 | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.935 |