node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACI18411.1 | ACI19247.1 | DICTH_0828 | DICTH_0821 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.586 |
ACI18411.1 | ACI19252.1 | DICTH_0828 | DICTH_0827 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase)(ppGpp synthetase I) ((P)ppGpp synthetase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.686 |
ACI18411.1 | ACI19717.1 | DICTH_0828 | DICTH_0820 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | Identified by match to protein family HMM PF00814. | 0.590 |
ACI18411.1 | ACI20029.1 | DICTH_0828 | DICTH_0823 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. | 0.586 |
ACI18411.1 | aspS | DICTH_0828 | DICTH_0824 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.592 |
ACI18411.1 | dtd | DICTH_0828 | DICTH_0826 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.686 |
ACI18411.1 | hisS | DICTH_0828 | DICTH_0825 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | histidyl-tRNA synthetase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. | 0.686 |
ACI18411.1 | purA | DICTH_0828 | DICTH_0822 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.586 |
ACI18411.1 | rimI | DICTH_0828 | DICTH_0819 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575. | 0.597 |
ACI18411.1 | tsaD | DICTH_0828 | DICTH_0818 | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | Sialoglycoprotease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.593 |
ACI19247.1 | ACI18411.1 | DICTH_0821 | DICTH_0828 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Permeases of the major facilitator superfamily; Identified by match to protein family HMM PF07690. | 0.586 |
ACI19247.1 | ACI19252.1 | DICTH_0821 | DICTH_0827 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase)(ppGpp synthetase I) ((P)ppGpp synthetase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.667 |
ACI19247.1 | ACI19717.1 | DICTH_0821 | DICTH_0820 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Identified by match to protein family HMM PF00814. | 0.990 |
ACI19247.1 | ACI20029.1 | DICTH_0821 | DICTH_0823 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. | 0.781 |
ACI19247.1 | aspS | DICTH_0821 | DICTH_0824 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.782 |
ACI19247.1 | dtd | DICTH_0821 | DICTH_0826 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.668 |
ACI19247.1 | hisS | DICTH_0821 | DICTH_0825 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | histidyl-tRNA synthetase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. | 0.710 |
ACI19247.1 | purA | DICTH_0821 | DICTH_0822 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.797 |
ACI19247.1 | rimI | DICTH_0821 | DICTH_0819 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575. | 0.802 |
ACI19247.1 | tsaD | DICTH_0821 | DICTH_0818 | Conserved hypothetical protein; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Sialoglycoprotease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.970 |