STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HVO_1799Digeranylgeranylglycerophospholipid reductase / dolichol omega-reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Can fully reduce the unsaturated isoprenoid side chains of membrane phospholipids and glycolipids. Is also able to reduce the omega-position isoprene of dolichol phosphate. (410 aa)    
Predicted Functional Partners:
ubiA2
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
 
 0.948
carS
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
  
 0.920
HVO_2732
FixC family protein.
 
 
 0.789
HVO_0396
FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase).
  
     0.680
etfB2
Electron transfer flavoprotein beta subunit.
 
 
 0.665
HVO_1800
Uncharacterized protein.
       0.651
etfB1
Electron transfer flavoprotein beta subunit.
  
 
 0.598
etfA2
Electron transfer flavoprotein alpha subunit.
 
 
 0.598
etfA1
Electron transfer flavoprotein alpha subunit.
 
 
 0.586
HVO_1801
Uncharacterized protein.
       0.508
Your Current Organism:
Haloferax volcanii
NCBI taxonomy Id: 309800
Other names: H. volcanii DS2, Haloferax volcanii ATCC 29605, Haloferax volcanii DS2, Haloferax volcanii DSM 3757, Haloferax volcanii str. DS2, Haloferax volcanii strain DS2
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.