node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HVO_1984A | aceA | HVO_1984A | HVO_1984 | Uncharacterized protein. | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 0.773 |
HVO_1984A | aceB1 | HVO_1984A | HVO_1983 | Uncharacterized protein. | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | 0.773 |
HVO_2671 | aceA | HVO_2671 | HVO_1984 | Aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase). | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 0.951 |
HVO_2671 | aceB1 | HVO_2671 | HVO_1983 | Aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase). | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | 0.911 |
HVO_2671 | kdgA1 | HVO_2671 | HVO_0950 | Aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase). | 2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type. | 0.900 |
aceA | HVO_1984A | HVO_1984 | HVO_1984A | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Uncharacterized protein. | 0.773 |
aceA | HVO_2671 | HVO_1984 | HVO_2671 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase). | 0.951 |
aceA | aceB1 | HVO_1984 | HVO_1983 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | 0.994 |
aceA | acs1 | HVO_1984 | HVO_0894 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | acyl-CoA synthetase. | 0.771 |
aceA | acs3 | HVO_1984 | HVO_1236 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | acyl-CoA synthetase. | 0.771 |
aceA | acs5 | HVO_1984 | HVO_1585 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | acyl-CoA synthetase. | 0.771 |
aceA | citB1 | HVO_1984 | HVO_1955 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Aconitate hydratase. | 0.949 |
aceA | citB2 | HVO_1984 | HVO_0541 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Aconitate hydratase. | 0.955 |
aceA | citZ | HVO_1984 | HVO_0466 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Citrate synthase; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle; Belongs to the citrate synthase family. | 0.989 |
aceA | kdgA1 | HVO_1984 | HVO_0950 | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type. | 0.900 |
aceB1 | HVO_1984A | HVO_1983 | HVO_1984A | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | Uncharacterized protein. | 0.773 |
aceB1 | HVO_2671 | HVO_1983 | HVO_2671 | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | Aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase). | 0.911 |
aceB1 | aceA | HVO_1983 | HVO_1984 | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 0.994 |
aceB1 | citZ | HVO_1983 | HVO_0466 | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | Citrate synthase; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle; Belongs to the citrate synthase family. | 0.674 |
aceB1 | kdgA1 | HVO_1983 | HVO_0950 | Malate synthase; Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA. | 2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type. | 0.900 |