STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sufS1Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Able to reassemble a removed [2Fe-2S] cluster of an apo-ferredoxin. Shows a selenocysteine lyase activity approximately 280-fold higher than its cysteine desulfurase activity. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. (426 aa)    
Predicted Functional Partners:
sufC
Fe-S cluster assembly ATPase SufC.
  
 0.995
iscU
Iron-sulfur cluster assembly protein.
 
 
 0.992
sufB1
SufB domain protein.
 
 0.988
sufB2
SufB domain protein.
 
 0.961
trxB3
Thioredoxin-disulfide reductase.
 
 
  0.919
trxB1
Thioredoxin-disulfide reductase.
  
 
  0.907
ubaA
SAMP-activating enzyme E1; Likely activates multiple ubiquitin-like SAMPs for protein conjugation as well as for sulfur transfer, via ATP-dependent adenylation at their C-terminus. In fact, it is required for the formation of all three SAMP1-, SAMP2- and SAMP3-protein conjugates, and for molybdenum cofactor (MoCo) biosynthesis and thiolation of tRNAs.
  
  
 0.616
moaE
Molybdopterin synthase catalytic subunit; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by the thiocarboxylated form of SAMP1 (Probable). In the C-terminal section; belongs to the MoaE family.
  
  
 0.587
mscS8
Mechanosensitive channel protein MscS.
       0.577
HVO_2676
HesB/IscA family iron-sulfur cluster assembly accessory protein.
  
 
 0.547
Your Current Organism:
Haloferax volcanii
NCBI taxonomy Id: 309800
Other names: H. volcanii DS2, Haloferax volcanii ATCC 29605, Haloferax volcanii DS2, Haloferax volcanii DSM 3757, Haloferax volcanii str. DS2, Haloferax volcanii strain DS2
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