node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HVO_0121 | serA1 | HVO_0121 | HVO_0122 | LysE family transport protein. | Putative D-2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.668 |
HVO_0121 | srp54 | HVO_0121 | HVO_0123 | LysE family transport protein. | Signal recognition particle 54K protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. | 0.480 |
hda1 | rpl6 | HVO_0522 | HVO_2548 | HdaI-type histone deacetylase. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.522 |
hda1 | serA1 | HVO_0522 | HVO_0122 | HdaI-type histone deacetylase. | Putative D-2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.599 |
hda1 | udk | HVO_0522 | HVO_2797 | HdaI-type histone deacetylase. | Uridine kinase. | 0.683 |
rpl13 | rpl16 | HVO_2778 | HVO_0484 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | 0.999 |
rpl13 | rpl2 | HVO_2778 | HVO_2561 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.999 |
rpl13 | rpl22 | HVO_2778 | HVO_2559 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.999 |
rpl13 | rpl6 | HVO_2778 | HVO_2548 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.999 |
rpl13 | rps15 | HVO_2778 | HVO_1148 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 30S ribosomal protein S15. | 0.999 |
rpl13 | serA1 | HVO_2778 | HVO_0122 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | Putative D-2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.502 |
rpl13 | srp54 | HVO_2778 | HVO_0123 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | Signal recognition particle 54K protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. | 0.999 |
rpl16 | rpl13 | HVO_0484 | HVO_2778 | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
rpl16 | rpl2 | HVO_0484 | HVO_2561 | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.999 |
rpl16 | rpl22 | HVO_0484 | HVO_2559 | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.999 |
rpl16 | rpl6 | HVO_0484 | HVO_2548 | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.999 |
rpl16 | rps15 | HVO_0484 | HVO_1148 | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | 30S ribosomal protein S15. | 0.999 |
rpl16 | serA1 | HVO_0484 | HVO_0122 | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | Putative D-2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.535 |
rpl16 | srp54 | HVO_0484 | HVO_0123 | 50S ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family. | Signal recognition particle 54K protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. | 0.999 |
rpl2 | rpl13 | HVO_2561 | HVO_2778 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |