STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HVO_1281Putative glycosyltransferase, type 1. (357 aa)    
Predicted Functional Partners:
HVO_1283
Oxidoreductase (homolog to zinc-containing alcohol dehydrogenase / threonine 3-dehydrogenase).
 
  
 0.923
HVO_1282
PtpS family protein.
 
     0.901
HVO_1135
Homolog to S-adenosylmethionine-dependent methyltransferase.
     0.775
gch3
GTP cyclohydrolase 3; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
       0.773
aglM
UDP-glucose 6-dehydrogenase AglM; Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Involved in the biosynthesis of the hexuronic acids found at both positions 2 and 3 of the pentasaccharide; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
  
 0.660
agl9
Low-salt glycan biosynthesis hexosyltransferase Agl9; Hexosyltransferase involved in N-glycan biosynthetic pathway that takes place under low-salt conditions (1.75 M instead of 3.4 M). Participates in the formation of the tetrasaccharide present at 'Asn- 532' of S-layer glycoprotein Csg, consisting of a sulfated hexose, 2 hexoses and rhamnose. Involved in the addition of sugar 3 to the disaccharide-charged dolichol phosphate in the tetrasaccharide. Belongs to the glycosyltransferase group 1 family.
 
     0.580
HVO_1285
Uncharacterized protein.
       0.574
HVO_2043
Putative glycosyltransferase, type 1.
 
     0.568
HVO_2538
Alpha/beta hydrolase fold protein.
   
 
 0.567
agl13
dTDP-4-dehydrorhamnose 3,5-epimerase; Epimerase involved in N-glycan biosynthetic pathway that takes place under low-salt conditions (1.75 M instead of 3.4 M). Participates in the formation of the tetrasaccharide present at 'Asn- 532' of S-layer glycoprotein Csg, consisting of a sulfated hexose, 2 hexoses and rhamnose. Involved in the addition of final rhamnose (sugar 4) of the tetrasaccharide on the dolichol phosphate carrier. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.538
Your Current Organism:
Haloferax volcanii
NCBI taxonomy Id: 309800
Other names: H. volcanii DS2, Haloferax volcanii ATCC 29605, Haloferax volcanii DS2, Haloferax volcanii DSM 3757, Haloferax volcanii str. DS2, Haloferax volcanii strain DS2
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