node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HVO_1105 | nusA | HVO_1105 | HVO_0351 | MiaB-like tRNA modifying enzyme. | Transcription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. | 0.521 |
HVO_1105 | tgtA1 | HVO_1105 | HVO_2001 | MiaB-like tRNA modifying enzyme. | tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. | 0.950 |
HVO_1105 | tiaS | HVO_1105 | HVO_0339 | MiaB-like tRNA modifying enzyme. | tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.694 |
HVO_1105 | trm56 | HVO_1105 | HVO_1173 | MiaB-like tRNA modifying enzyme. | tRNA (cytidine(56)-2'-O)-methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.720 |
HVO_1870 | arcS | HVO_1870 | HVO_2008 | M50 family metalloprotease. | Archaeosine synthase; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. | 0.691 |
HVO_1870 | cbf5 | HVO_1870 | HVO_2493 | M50 family metalloprotease. | tRNA/rRNA pseudouridine synthase Cbf5; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.482 |
HVO_1870 | nusA | HVO_1870 | HVO_0351 | M50 family metalloprotease. | Transcription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. | 0.612 |
HVO_1870 | tgtA1 | HVO_1870 | HVO_2001 | M50 family metalloprotease. | tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. | 0.570 |
HVO_2002 | tgtA1 | HVO_2002 | HVO_2001 | ArsR family transcription regulator. | tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. | 0.567 |
arcS | HVO_1870 | HVO_2008 | HVO_1870 | Archaeosine synthase; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. | M50 family metalloprotease. | 0.691 |
arcS | cbf5 | HVO_2008 | HVO_2493 | Archaeosine synthase; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. | tRNA/rRNA pseudouridine synthase Cbf5; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.625 |
arcS | nusA | HVO_2008 | HVO_0351 | Archaeosine synthase; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. | Transcription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. | 0.448 |
arcS | tgtA1 | HVO_2008 | HVO_2001 | Archaeosine synthase; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. | tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. | 0.649 |
arcS | tiaS | HVO_2008 | HVO_0339 | Archaeosine synthase; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. | tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.630 |
cbf5 | HVO_1870 | HVO_2493 | HVO_1870 | tRNA/rRNA pseudouridine synthase Cbf5; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | M50 family metalloprotease. | 0.482 |
cbf5 | arcS | HVO_2493 | HVO_2008 | tRNA/rRNA pseudouridine synthase Cbf5; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | Archaeosine synthase; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. | 0.625 |
cbf5 | nusA | HVO_2493 | HVO_0351 | tRNA/rRNA pseudouridine synthase Cbf5; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | Transcription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. | 0.938 |
cbf5 | tgtA1 | HVO_2493 | HVO_2001 | tRNA/rRNA pseudouridine synthase Cbf5; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. | 0.531 |
htr7 | tgtA1 | HVO_1999 | HVO_2001 | Transducer protein Htr7. | tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. | 0.501 |
nusA | HVO_1105 | HVO_0351 | HVO_1105 | Transcription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. | MiaB-like tRNA modifying enzyme. | 0.521 |