STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_0560Hydrolase, alpha/beta fold family; Identified by match to protein family HMM PF00561. (278 aa)    
Predicted Functional Partners:
sucB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
   
 
 0.783
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.
   
   0.729
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.727
trd_1390
Putative hydrolase, alpha/beta fold family; Identified by match to protein family HMM PF00561.
  
     0.651
trd_0563
Putative FAD binding domain; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494.
 
  
 0.627
trd_0039
acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028.
   
 
 0.479
trd_0116
acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028.
   
 
 0.479
trd_1340
acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028.
   
 
 0.479
trd_1126
Sulfide dehydrogenase; Identified by match to protein family HMM PF07992.
   
 
 0.467
trd_0559
Probable acetolactate synthase large subunit; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
     
 0.448
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.