STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_1162Protein of unknown function (DUF422) family; Identified by match to protein family HMM PF04240. (523 aa)    
Predicted Functional Partners:
trd_1161
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
 
   
 0.958
trd_1159
Phytoene synthetase; Identified by match to protein family HMM PF00494.
   
 0.905
trd_1163
Phytoene dehydrogenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01593; match to protein family HMM TIGR02734.
 
   
 0.859
trd_1160
Conserved hypothetical protein.
     
 0.813
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.787
trd_1144
Conserved hypothetical protein.
  
     0.671
trd_0866
Conserved hypothetical protein.
  
     0.645
trd_1165
Glycolate oxidase subunit; Identified by match to protein family HMM PF00037; match to protein family HMM PF01565; match to protein family HMM PF02754; match to protein family HMM PF02913.
     
 0.641
trd_0868
Conserved hypothetical protein.
  
     0.609
trd_0005
Tetratricopeptide repeat family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721.
  
     0.592
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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