STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (390 aa)    
Predicted Functional Partners:
trd_0160
Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family.
   
 0.990
trd_1635
Transcriptional regulator superfamily; Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738.
  
 0.984
trd_1568
Putative molybdopterin biosynthesis MoeB protein; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.
   
 0.971
trd_0377
SUF system FeS assembly protein, NifU family; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994.
 
 0.961
trd_1173
Identified by match to protein family HMM PF01592.
 
 0.957
trd_0384
Identified by match to protein family HMM PF01592.
  
 0.950
trd_1309
Molybdopterin biosynthesis protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.
   
 0.935
trd_0517
3-mercaptopyruvate sulfurtransferase; Identified by match to protein family HMM PF00581.
   
 0.917
trd_1172
Putative thiosulfate sulfurtransferase precursor; Identified by match to protein family HMM PF00581.
   
 0.917
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
    
 0.917
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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