STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_1931Alpha amylase, catalytic subdomain; Identified by match to protein family HMM PF00128; match to protein family HMM TIGR02456; match to protein family HMM TIGR02457. (1123 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 
 0.995
treY
Putative fusion of 4-alpha glucanotransferase and maltooligosyltrehalose synthase; Identified by match to protein family HMM PF02446.
 
 0.993
glgE
Possible glycanase or glycogenase with amylase domain; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
 0.991
trd_0082
alpha-D-1,4-glucosidase; Identified by match to protein family HMM PF00128.
 
0.972
otsB
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.960
trd_1824
Glycosyl hydrolase, family 15; Identified by match to protein family HMM PF00723.
    
 0.946
trd_0944
Putative trehalose phosphorylase; Identified by match to protein family HMM PF00534.
   
 0.917
trd_1935
Glycosyl hydrolase, family 57; Identified by match to protein family HMM PF03065.
 
   
 0.886
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
  
 0.829
trd_0080
Putative integral membrane protein.
   
 0.708
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
Server load: medium (42%) [HD]