STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)    
Predicted Functional Partners:
tpiA
Bifunctional PGK/TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.999
pgk
Bifunctional PGK/TIM; Belongs to the phosphoglycerate kinase family.
 
 
 0.999
CTN_0477
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.992
CTN_1898
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.986
CTN_1587
Helicase domain protein.
  
 
 0.983
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.977
CTN_0412
Fructose-bisphosphate aldolase.
  
 0.975
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.953
CTN_0952
Transketolase.
   
 0.931
CTN_0413
Pyruvate,orthophosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.926
Your Current Organism:
Thermotoga neapolitana
NCBI taxonomy Id: 309803
Other names: T. neapolitana DSM 4359, Thermotoga neapolitana ATCC 49049, Thermotoga neapolitana DSM 4359, Thermotoga neapolitana JCM 10099, Thermotoga neapolitana NS-E
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