STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
c8aComplement component 8, alpha polypeptide. (598 aa)    
Predicted Functional Partners:
c8g
Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family.
  
 0.992
c9
Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC; Belongs to the complement C6/C7/C8/C9 family.
   
0.975
c6
Complement component 6.
   
 
0.881
c8b
Complement component 8, beta polypeptide.
  
0.730
LOC101064033
Si:ch1073-280e3.1; Belongs to the peptidase S1 family.
   
 
 0.693
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
   
  
 0.642
cpb2
Carboxypeptidase B2 (plasma).
   
  
 0.601
LOC101063812
Vitronectin b.
   
 0.566
LOC101069732
Voltage-dependent anion channel 2.
     
  0.540
LOC101066455
Complement component 7a.
   
 
 
0.540
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.