node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Avi_0598 | Avi_3985 | Avi_0598 | Avi_3985 | acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | AMP-(fatty) acid ligase protein. | 0.937 |
Avi_0598 | acs | Avi_0598 | Avi_4377 | acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.937 |
Avi_0598 | cisY | Avi_0598 | Avi_2563 | acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.938 |
Avi_0598 | glcB | Avi_0598 | Avi_0057 | acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.932 |
Avi_0598 | maeB | Avi_0598 | Avi_1891 | acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | NADP-dependent malic enzyme. | 0.516 |
Avi_2076 | Avi_3985 | Avi_2076 | Avi_3985 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | AMP-(fatty) acid ligase protein. | 0.608 |
Avi_2076 | aceA | Avi_2076 | Avi_0816 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Isocitrate lyase. | 0.471 |
Avi_2076 | acs | Avi_2076 | Avi_4377 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.608 |
Avi_2076 | cisY | Avi_2076 | Avi_2563 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.971 |
Avi_2076 | fumC | Avi_2076 | Avi_2077 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.984 |
Avi_2076 | glcB | Avi_2076 | Avi_0057 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.940 |
Avi_2076 | glcF | Avi_2076 | Avi_5789 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycolate oxidase iron-sulfur subunit. | 0.460 |
Avi_2076 | maeB | Avi_2076 | Avi_1891 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NADP-dependent malic enzyme. | 0.969 |
Avi_2076 | mdh-2 | Avi_2076 | Avi_4129 | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.992 |
Avi_3985 | Avi_0598 | Avi_3985 | Avi_0598 | AMP-(fatty) acid ligase protein. | acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.937 |
Avi_3985 | Avi_2076 | Avi_3985 | Avi_2076 | AMP-(fatty) acid ligase protein. | Fumarate hydratase protein class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.608 |
Avi_3985 | aceA | Avi_3985 | Avi_0816 | AMP-(fatty) acid ligase protein. | Isocitrate lyase. | 0.425 |
Avi_3985 | acs | Avi_3985 | Avi_4377 | AMP-(fatty) acid ligase protein. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.914 |
Avi_3985 | cisY | Avi_3985 | Avi_2563 | AMP-(fatty) acid ligase protein. | Citrate synthase; Belongs to the citrate synthase family. | 0.974 |
Avi_3985 | glcB | Avi_3985 | Avi_0057 | AMP-(fatty) acid ligase protein. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.961 |