node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arad_1458 | clpB | Arad_1458 | Arad_4124 | Molecular chaperone protein. | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.573 |
Arad_1458 | dnaK | Arad_1458 | Arad_0212 | Molecular chaperone protein. | Chaperone protein (Heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.948 |
Arad_1458 | groEL | Arad_1458 | Arad_1067 | Molecular chaperone protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.699 |
Arad_1458 | groL | Arad_1458 | Arad_8744 | Molecular chaperone protein. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.697 |
Arad_1458 | grpE | Arad_1458 | Arad_0614 | Molecular chaperone protein. | Molecular chaperone heat shock protein (hsp-70); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle [...] | 0.787 |
Arad_1458 | grpE-2 | Arad_1458 | Arad_7914 | Molecular chaperone protein. | Molecular chaperone heat shock protein (hsp-70); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle [...] | 0.776 |
Arad_1458 | htpG | Arad_1458 | Arad_8710 | Molecular chaperone protein. | Heat shock chaperone protein; Molecular chaperone. Has ATPase activity. | 0.867 |
clpB | Arad_1458 | Arad_4124 | Arad_1458 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone protein. | 0.573 |
clpB | dnaJ | Arad_4124 | Arad_7920 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | DNAJ molecular chaperone protein. | 0.667 |
clpB | dnaJ1 | Arad_4124 | Arad_0210 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between Dn [...] | 0.667 |
clpB | dnaJ2 | Arad_4124 | Arad_1218 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone protein. | 0.656 |
clpB | dnaK | Arad_4124 | Arad_0212 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein (Heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.946 |
clpB | groEL | Arad_4124 | Arad_1067 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.705 |
clpB | groL | Arad_4124 | Arad_8744 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.705 |
clpB | grpE | Arad_4124 | Arad_0614 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone heat shock protein (hsp-70); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle [...] | 0.777 |
clpB | grpE-2 | Arad_4124 | Arad_7914 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone heat shock protein (hsp-70); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle [...] | 0.777 |
clpB | htpG | Arad_4124 | Arad_8710 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock chaperone protein; Molecular chaperone. Has ATPase activity. | 0.772 |
dnaJ | clpB | Arad_7920 | Arad_4124 | DNAJ molecular chaperone protein. | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.667 |
dnaJ | dnaK | Arad_7920 | Arad_0212 | DNAJ molecular chaperone protein. | Chaperone protein (Heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.984 |
dnaJ | groEL | Arad_7920 | Arad_1067 | DNAJ molecular chaperone protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.832 |