STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q22AK0_TETTSDynamin central region family protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (718 aa)    
Predicted Functional Partners:
I7LUR8_TETTS
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.724
Q22ZA7_TETTS
PX-SNX-like domain protein.
    
 0.688
I7MH35_TETTS
Zinc finger, C3HC4 type (RING finger) protein.
   
 0.660
I7M0G3_TETTS
Uncharacterized protein.
    
 
 0.580
Q22E31_TETTS
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.577
Q22V00_TETTS
Clathrin adapter protein AP-1, mu subunit; Belongs to the adaptor complexes medium subunit family.
    
 0.563
W7XKA5_TETTS
ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPase family protein; Belongs to the small GTPase superfamily. Arf family.
 
 
 0.552
Q23WW4_TETTS
Uncharacterized protein.
   
 0.548
Q23WP4_TETTS
SH3 domain-containing protein.
    
 
 0.546
Q22NU2_TETTS
WH1 domain protein.
     
 0.538
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.