STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q22C20_TETTSHelicase carboxy-terminal domain protein. (1157 aa)    
Predicted Functional Partners:
I7MLW8_TETTS
Type III restriction enzyme, res subunit.
   
 0.754
Q245U8_TETTS
Uncharacterized protein.
    
 0.664
Q22BB4_TETTS
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.658
I7M260_TETTS
Actin; Belongs to the actin family.
    
 0.644
I7LV38_TETTS
RuvB-like helicase; Belongs to the RuvB family.
    
 0.641
I7M6R9_TETTS
DNA-directed RNA polymerase subunit K.
   
 0.631
A4VDR4_TETTS
Conjugation stage-specific protein.
   
 0.600
Q235X0_TETTS
DNA-directed RNA polymerase I and III subunit RPAC1.
   
 0.600
I7MFS9_TETTS
Small ubiquitin-related modifier.
    
 0.596
HTA3
Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, preferentially in transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Essential for vegetative growth.
    
 0.583
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.