STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q22XS0_TETTSD-beta-hydroxybutyrate dehydrogenase. (263 aa)    
Predicted Functional Partners:
I7MJQ6_TETTS
3-oxoacyl-(Acyl carrier) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.829
Q23FU4_TETTS
Oxidoreductase (Short-chain dehydrogenase family).
  
0.762
Q22KR8_TETTS
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 
 0.658
Q23YB7_TETTS
Peroxisomal 3-ketoacyl-CoA thiolase B; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.652
Q22KI6_TETTS
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.629
Q23CU4_TETTS
V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
  
 0.627
I7M046_TETTS
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
 
 0.625
Q22HD5_TETTS
Mevalonate kinase.
      
 0.612
Q22RY4_TETTS
Enoyl-(Acyl carrier) reductase.
  
 
0.611
Q235W7_TETTS
Short-chain dehydrogenase/reductase SDR.
  
 
0.611
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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