STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Q23K67_TETTSProbable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (342 aa)    
Predicted Functional Partners:
Q23A85_TETTS
MMS19 nucleotide excision repair-like protein, putative.
    
 0.998
I7LXL0_TETTS
MIP18 family protein FAM96A, putative.
    
 0.983
I7M608_TETTS
Mitotic spindle-associated MMXD complex subunit MIP18, putative.
    
 0.983
Q22NP0_TETTS
Iron only hydrogenase large subunit, carboxy-terminal domain protein; Belongs to the NARF family.
    
 0.922
I7LXA1_TETTS
Helicase carboxy-terminal domain protein.
    
 0.746
I7M2Q2_TETTS
DNA repair helicase.
    
 0.746
Q22KQ8_TETTS
Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
 
  
 0.720
I7LXH9_TETTS
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
      
 0.662
I7M713_TETTS
CobQ/CobB/MinD/ParA nucleotide-binding domain protein.
    
 0.621
I7M9Z1_TETTS
DNA polymerase family B exonuclease domain protein.
    
 0.579
Your Current Organism:
Tetrahymena thermophila
NCBI taxonomy Id: 312017
Other names: T. thermophila SB210, Tetrahymena thermophila SB210
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