STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR25007.1Glycerol uptake facilitator, MIP channel; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. (252 aa)    
Predicted Functional Partners:
EAR25004.1
Phosphoenolpyruvate-protein phosphotransferase; COG3412 Uncharacterized protein conserved in bacteria.
 
  
 0.909
EAR25005.1
COG2376 Dihydroxyacetone kinase.
 
  
 0.857
EAR25006.1
Conserved protein with kinase domain of diacylglycerol kinase; COG2376 Dihydroxyacetone kinase.
 
  
 0.855
EAR26034.1
Transcriptional regulator, Crp/Fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.
   
 0.802
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.708
glpK-2
Glycerol kinase 2; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.708
EAR25487.1
COG0105 Nucleoside diphosphate kinase.
  
 
 0.693
EAR25102.1
COG0631 Serine/threonine protein phosphatase.
    
   0.669
EAR26181.1
COG0631 Serine/threonine protein phosphatase.
    
   0.669
dnaJ
DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
    
 
 0.656
Your Current Organism:
actinobacterium PHSC20C1
NCBI taxonomy Id: 312284
Other names: m. actinobacterium PHSC20C1, marine actinobacterium PHSC20C1, marine actinobacterium str. PHSC20C1, marine actinobacterium strain PHSC20C1
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