| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| frsA | gpt | VF_0739 | VF_0738 | Hydrolase, binds to enzyme IIA(Glc); Belongs to the UPF0255 family. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.514 |
| frsA | yieG | VF_0739 | VF_0737 | Hydrolase, binds to enzyme IIA(Glc); Belongs to the UPF0255 family. | Predicted inner membrane protein. | 0.452 |
| gpt | frsA | VF_0738 | VF_0739 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Hydrolase, binds to enzyme IIA(Glc); Belongs to the UPF0255 family. | 0.514 |
| gpt | guaA | VF_0738 | VF_0638 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.989 |
| gpt | purC | VF_0738 | VF_1498 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.418 |
| gpt | purE | VF_0738 | VF_2537 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.457 |
| gpt | purK | VF_0738 | VF_2538 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.483 |
| gpt | purL | VF_0738 | VF_0652 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.772 |
| gpt | purM | VF_0738 | VF_1928 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Phosphoribosylaminoimidazole synthetase. | 0.474 |
| gpt | yieG | VF_0738 | VF_0737 | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Predicted inner membrane protein. | 0.757 |
| guaA | gpt | VF_0638 | VF_0738 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.989 |
| guaA | purC | VF_0638 | VF_1498 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.679 |
| guaA | purD | VF_0638 | VF_2395 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.909 |
| guaA | purE | VF_0638 | VF_2537 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.585 |
| guaA | purK | VF_0638 | VF_2538 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.712 |
| guaA | purL | VF_0638 | VF_0652 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.982 |
| guaA | purM | VF_0638 | VF_1928 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole synthetase. | 0.611 |
| guaA | uraA | VF_0638 | VF_1926 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Uracil transporter. | 0.478 |
| guaA | yieG | VF_0638 | VF_0737 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Predicted inner membrane protein. | 0.473 |
| purC | gpt | VF_1498 | VF_0738 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.418 |