node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VF_1288 | VF_1290 | VF_1288 | VF_1290 | Glutaredoxin-like domain. | Hypothetical protein. | 0.797 |
VF_1288 | rlmL | VF_1288 | VF_1287 | Glutaredoxin-like domain. | Predicted methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.810 |
VF_1288 | uup | VF_1288 | VF_1289 | Glutaredoxin-like domain. | Fused predicted transporter subunits of ABC superfamily: ATP-binding components. | 0.804 |
VF_1290 | VF_1288 | VF_1290 | VF_1288 | Hypothetical protein. | Glutaredoxin-like domain. | 0.797 |
VF_1290 | rlmL | VF_1290 | VF_1287 | Hypothetical protein. | Predicted methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.816 |
VF_1290 | uup | VF_1290 | VF_1289 | Hypothetical protein. | Fused predicted transporter subunits of ABC superfamily: ATP-binding components. | 0.797 |
birA | rlmL | VF_2425 | VF_1287 | BirA transcriptional repressor, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Predicted methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.593 |
ispU | pnp | VF_1958 | VF_0490 | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.717 |
ispU | pyrG | VF_1958 | VF_2076 | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.638 |
ispU | rlmL | VF_1958 | VF_1287 | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | Predicted methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.610 |
ispU | rsmB | VF_1958 | VF_2545 | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.451 |
pnp | ispU | VF_0490 | VF_1958 | Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.717 |
pnp | pyrG | VF_0490 | VF_2076 | Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.851 |
pnp | rlmL | VF_0490 | VF_1287 | Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Predicted methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.597 |
pnp | rsmB | VF_0490 | VF_2545 | Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.428 |
pnp | rsmF | VF_0490 | VF_1274 | Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Predicted methyltransferase; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.435 |
pyrG | ispU | VF_2076 | VF_1958 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.638 |
pyrG | pnp | VF_2076 | VF_0490 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.851 |
pyrG | rlmL | VF_2076 | VF_1287 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Predicted methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.581 |
pyrG | rsmB | VF_2076 | VF_2545 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.511 |