node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VF_1108 | clpA | VF_1108 | VF_1765 | Chaperone protein DnaJ-like protein. | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Belongs to the ClpA/ClpB family. | 0.636 |
VF_1108 | clpB | VF_1108 | VF_0566 | Chaperone protein DnaJ-like protein. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.636 |
VF_1108 | dnaK | VF_1108 | VF_1994 | Chaperone protein DnaJ-like protein. | Chaperone Hsp70/DnaK, co-chaperone with DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.937 |
VF_1108 | dnaK1 | VF_1108 | VF_1467 | Chaperone protein DnaJ-like protein. | Chaperone, DnaK-like protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.936 |
VF_1108 | groL | VF_1108 | VF_0205 | Chaperone protein DnaJ-like protein. | Cpn60 chaperonin GroEL, large subunit of GroESL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.770 |
VF_1108 | groS | VF_1108 | VF_0204 | Chaperone protein DnaJ-like protein. | Cpn10 chaperonin GroES, small subunit of GroESL; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.627 |
VF_1108 | grpE | VF_1108 | VF_1996 | Chaperone protein DnaJ-like protein. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.946 |
VF_1108 | htpG | VF_1108 | VF_0792 | Chaperone protein DnaJ-like protein. | Molecular chaperone HSP90 family; Molecular chaperone. Has ATPase activity. | 0.863 |
VF_1477 | clpA | VF_1477 | VF_1765 | Tetratricopeptide repeat family protein. | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Belongs to the ClpA/ClpB family. | 0.701 |
VF_1477 | clpB | VF_1477 | VF_0566 | Tetratricopeptide repeat family protein. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.662 |
VF_1477 | dnaK | VF_1477 | VF_1994 | Tetratricopeptide repeat family protein. | Chaperone Hsp70/DnaK, co-chaperone with DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.886 |
VF_1477 | dnaK1 | VF_1477 | VF_1467 | Tetratricopeptide repeat family protein. | Chaperone, DnaK-like protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.886 |
VF_1477 | groL | VF_1477 | VF_0205 | Tetratricopeptide repeat family protein. | Cpn60 chaperonin GroEL, large subunit of GroESL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.716 |
VF_1477 | groS | VF_1477 | VF_0204 | Tetratricopeptide repeat family protein. | Cpn10 chaperonin GroES, small subunit of GroESL; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.583 |
VF_1477 | grpE | VF_1477 | VF_1996 | Tetratricopeptide repeat family protein. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.777 |
VF_1477 | htpG | VF_1477 | VF_0792 | Tetratricopeptide repeat family protein. | Molecular chaperone HSP90 family; Molecular chaperone. Has ATPase activity. | 0.924 |
clpA | VF_1108 | VF_1765 | VF_1108 | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ-like protein. | 0.636 |
clpA | VF_1477 | VF_1765 | VF_1477 | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Belongs to the ClpA/ClpB family. | Tetratricopeptide repeat family protein. | 0.701 |
clpA | dnaJ | VF_1765 | VF_1993 | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Belongs to the ClpA/ClpB family. | Chaperone Hsp40/DnaJ, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent intera [...] | 0.758 |
clpA | dnaK | VF_1765 | VF_1994 | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Belongs to the ClpA/ClpB family. | Chaperone Hsp70/DnaK, co-chaperone with DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.858 |