node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VF_A0917 | cdd | VF_A0917 | VF_1485 | Deoxycytidylate deaminase. | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.400 |
VF_A0917 | tdk | VF_A0917 | VF_1599 | Deoxycytidylate deaminase. | Thymidine kinase/deoxyuridine kinase. | 0.934 |
VF_A0917 | thyA | VF_A0917 | VF_0460 | Deoxycytidylate deaminase. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.943 |
VF_A0917 | tmk | VF_A0917 | VF_1735 | Deoxycytidylate deaminase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.946 |
VF_A0917 | ushA | VF_A0917 | VF_0778 | Deoxycytidylate deaminase. | Bifunctional UDP-sugar hydrolase/5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.901 |
VF_A0917 | yjjG | VF_A0917 | VF_A0293 | Deoxycytidylate deaminase. | dUMP phosphatase. | 0.911 |
cdd | VF_A0917 | VF_1485 | VF_A0917 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Deoxycytidylate deaminase. | 0.400 |
cdd | deoA | VF_1485 | VF_0505 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.967 |
cdd | deoD | VF_1485 | VF_0507 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Purine-nucleoside phosphorylase. | 0.915 |
cdd | deoD2 | VF_1485 | VF_A0402 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Purine nucleoside phosphorylase deoD-type 2. | 0.915 |
cdd | deoD3 | VF_1485 | VF_A0968 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Purine nucleoside phosphorylase deoD-type; PNP. | 0.915 |
cdd | tdk | VF_1485 | VF_1599 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Thymidine kinase/deoxyuridine kinase. | 0.940 |
cdd | ushA | VF_1485 | VF_0778 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Bifunctional UDP-sugar hydrolase/5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.906 |
cdd | yjjG | VF_1485 | VF_A0293 | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | dUMP phosphatase. | 0.901 |
deoA | cdd | VF_0505 | VF_1485 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.967 |
deoA | deoD | VF_0505 | VF_0507 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Purine-nucleoside phosphorylase. | 0.683 |
deoA | tdk | VF_0505 | VF_1599 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Thymidine kinase/deoxyuridine kinase. | 0.934 |
deoA | thyA | VF_0505 | VF_0460 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.425 |
deoA | ushA | VF_0505 | VF_0778 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Bifunctional UDP-sugar hydrolase/5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.921 |
deoA | yjjG | VF_0505 | VF_A0293 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | dUMP phosphatase. | 0.902 |