node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VF_1531 | cobA | VF_1531 | VF_0773 | Ferrochelatase. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.992 |
VF_1531 | hemA | VF_1531 | VF_0767 | Ferrochelatase. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.684 |
VF_1531 | hemB | VF_1531 | VF_0053 | Ferrochelatase. | Porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | 0.855 |
VF_1531 | hemC | VF_1531 | VF_0066 | Ferrochelatase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.908 |
VF_1531 | hemE | VF_1531 | VF_2402 | Ferrochelatase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.481 |
VF_1531 | hemL | VF_1531 | VF_2135 | Ferrochelatase. | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.768 |
alr | ftsA | VF_0302 | VF_2197 | Alanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | ATP-binding cell division protein involved in recruitment of FtsK to Z ring; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.570 |
alr | ftsQ | VF_0302 | VF_2199 | Alanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.621 |
alr | hemL | VF_0302 | VF_2135 | Alanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.708 |
alr | murI | VF_0302 | VF_2433 | Alanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.795 |
cobA | VF_1531 | VF_0773 | VF_1531 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Ferrochelatase. | 0.992 |
cobA | hemA | VF_0773 | VF_0767 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.806 |
cobA | hemB | VF_0773 | VF_0053 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | 0.879 |
cobA | hemC | VF_0773 | VF_0066 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.989 |
cobA | hemE | VF_0773 | VF_2402 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.922 |
cobA | hemL | VF_0773 | VF_2135 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.759 |
ftsA | alr | VF_2197 | VF_0302 | ATP-binding cell division protein involved in recruitment of FtsK to Z ring; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Alanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.570 |
ftsA | ftsQ | VF_2197 | VF_2199 | ATP-binding cell division protein involved in recruitment of FtsK to Z ring; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.993 |
ftsA | hemL | VF_2197 | VF_2135 | ATP-binding cell division protein involved in recruitment of FtsK to Z ring; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Glutamate-1-semialdehyde aminotransferase (aminomutase). | 0.598 |
ftsA | murI | VF_2197 | VF_2433 | ATP-binding cell division protein involved in recruitment of FtsK to Z ring; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.726 |