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pafA protein (Janibacter sp. HTCC2649) - STRING interaction network
"pafA" - Pup-conjugating enzyme in Janibacter sp. HTCC2649
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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pafAPup-conjugating enzyme ; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (453 aa)    
Predicted Functional Partners:
prcA
Proteasome core protein PrcA ; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (265 aa)
   
  0.974
JNB_03035
AAA ATPase forming ring-shaped complexes (553 aa)
 
     
  0.952
prcB
Proteasome core protein PrcB ; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (280 aa)
 
   
  0.938
JNB_02965
Uncharacterized protein ; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (63 aa)
 
          0.808
JNB_02935
Peptidyl-prolyl cis-trans isomerase (314 aa)
              0.754
JNB_14908
Uncharacterized protein (212 aa)
   
        0.747
JNB_19098
Uncharacterized protein (333 aa)
   
        0.704
mca
Mycothiol S-conjugate amidase ; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics (313 aa)
   
        0.694
JNB_04555
Uncharacterized protein (146 aa)
   
          0.691
JNB_02930
Peptidyl-prolyl cis-trans isomerase (128 aa)
              0.677
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649, Janibacter, Janibacter HTCC2649, Janibacter sp. HTCC2649
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