Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (140 aa)
Predicted Functional Partners:
Putative transporter (391 aa)
Putative oxidoreductase (353 aa)
Probable conserved membrane protein (336 aa)
Putative hydrolase (263 aa)
Uncharacterized protein (226 aa)
Possible conserved transmembrane protein (203 aa)
DNA gyrase subunit A ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (921 aa)
DNA topoisomerase (ATP-hydrolyzing) (816 aa)
Two-component system, regulatory protein (215 aa)
Putative two-component system response regulator (202 aa)
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589 Other names: J. sp. HTCC2649, Janibacter, Janibacter HTCC2649, Janibacter sp. HTCC2649