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leuB protein (Janibacter sp. HTCC2649) - STRING interaction network
"leuB" - Beta-IPM dehydrogenase in Janibacter sp. HTCC2649
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
leuBBeta-IPM dehydrogenase ; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (361 aa)    
Predicted Functional Partners:
leuC
Isopropylmalate isomerase ; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (482 aa)
 
  0.998
leuD
Isopropylmalate isomerase ; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (195 aa)
 
  0.994
JNB_19393
Putative 2-isopropylmalate synthase (537 aa)
 
  0.978
JNB_03815
Putative glutamate synthase (NADPH) large subunit (1514 aa)
   
 
  0.977
leuA
Alpha-isopropylmalate synthase ; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (579 aa)
 
  0.976
kgd
Alpha-ketoglutarate decarboxylase (1281 aa)
   
  0.969
JNB_19268
Acetolactate synthase (629 aa)
 
  0.966
JNB_19318
Branched-chain-amino-acid aminotransferase (365 aa)
   
 
  0.948
JNB_16689
Putative hydroxymethylglutaryl-CoA lyase (311 aa)
   
  0.933
ilvA
Threonine deaminase ; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (512 aa)
 
 
  0.918
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649, Janibacter, Janibacter HTCC2649, Janibacter sp. HTCC2649
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