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infB protein (Janibacter sp. HTCC2649) - STRING interaction network
"infB" - Translation initiation factor IF-2 in Janibacter sp. HTCC2649
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
infBTranslation initiation factor IF-2 ; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (789 aa)    
Predicted Functional Partners:
infA
Translation initiation factor IF-1 ; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex (73 aa)
     
  0.980
rpsB
30S ribosomal protein S2 (319 aa)
 
  0.957
rpsC
30S ribosomal protein S3 ; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (272 aa)
     
  0.956
infC
Translation initiation factor IF-3 ; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (289 aa)
   
  0.932
truB
tRNA-uridine isomerase ; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (312 aa)
 
 
  0.932
rpsE
30S ribosomal protein S5 ; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (223 aa)
     
  0.930
rpsM
30S ribosomal protein S13 ; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P- sites (125 aa)
     
  0.919
rbfA
Ribosome-binding factor A ; Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5’-terminal helix region of 16S rRNA (169 aa)
   
   
  0.907
nusA
Transcription termination/antitermination protein NusA ; Participates in both transcription termination and antitermination (385 aa)
   
 
  0.899
rpsS
30S ribosomal protein S19 ; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (93 aa)
     
  0.890
Your Current Organism:
Janibacter sp. HTCC2649
NCBI taxonomy Id: 313589
Other names: J. sp. HTCC2649, Janibacter, Janibacter HTCC2649, Janibacter sp. HTCC2649
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