node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ELI_03910 | dapF | ELI_03910 | ELI_03915 | Hypothetical protein; COG0621 2-methylthioadenine synthetase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.857 |
ELI_03910 | ftsY | ELI_03910 | ELI_03905 | Hypothetical protein; COG0621 2-methylthioadenine synthetase. | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.866 |
ELI_06865 | asd | ELI_06865 | ELI_07430 | Ornithine/diaminopimelate/arginine decarboxylase,family 2; COG0019 Diaminopimelate decarboxylase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.440 |
ELI_06865 | dapF | ELI_06865 | ELI_03915 | Ornithine/diaminopimelate/arginine decarboxylase,family 2; COG0019 Diaminopimelate decarboxylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.934 |
ELI_06865 | lysA | ELI_06865 | ELI_02025 | Ornithine/diaminopimelate/arginine decarboxylase,family 2; COG0019 Diaminopimelate decarboxylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.926 |
ELI_06865 | murE | ELI_06865 | ELI_01770 | Ornithine/diaminopimelate/arginine decarboxylase,family 2; COG0019 Diaminopimelate decarboxylase. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.908 |
ELI_12125 | asd | ELI_12125 | ELI_07430 | COG0067 Glutamate synthase domain 1. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.656 |
ELI_12125 | carB | ELI_12125 | ELI_05695 | COG0067 Glutamate synthase domain 1. | COG0458 Carbamoylphosphate synthase large subunit; Belongs to the CarB family. | 0.972 |
ELI_12125 | dapF | ELI_12125 | ELI_03915 | COG0067 Glutamate synthase domain 1. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.731 |
ELI_12125 | murE | ELI_12125 | ELI_01770 | COG0067 Glutamate synthase domain 1. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.479 |
asd | ELI_06865 | ELI_07430 | ELI_06865 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Ornithine/diaminopimelate/arginine decarboxylase,family 2; COG0019 Diaminopimelate decarboxylase. | 0.440 |
asd | ELI_12125 | ELI_07430 | ELI_12125 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | COG0067 Glutamate synthase domain 1. | 0.656 |
asd | dapF | ELI_07430 | ELI_03915 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.796 |
asd | lysA | ELI_07430 | ELI_02025 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.537 |
carB | ELI_12125 | ELI_05695 | ELI_12125 | COG0458 Carbamoylphosphate synthase large subunit; Belongs to the CarB family. | COG0067 Glutamate synthase domain 1. | 0.972 |
carB | dapF | ELI_05695 | ELI_03915 | COG0458 Carbamoylphosphate synthase large subunit; Belongs to the CarB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.824 |
dapE | dapF | ELI_10605 | ELI_03915 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.934 |
dapE | rppH | ELI_10605 | ELI_07080 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Hydrolase, NUDIX family, NudH subfamily; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.432 |
dapF | ELI_03910 | ELI_03915 | ELI_03910 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Hypothetical protein; COG0621 2-methylthioadenine synthetase. | 0.857 |
dapF | ELI_06865 | ELI_03915 | ELI_06865 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Ornithine/diaminopimelate/arginine decarboxylase,family 2; COG0019 Diaminopimelate decarboxylase. | 0.934 |